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3,4 methylenedioxymethamphetamine (MDMA) is a psychoactive, synthetic drug chemically similar to the stimulant methamphetamine and the hallucinogen. This drug is commonly known by the names Ecstasy, Adam, hug, beans, and love drug. MDMA have been declared as an illegal drug which acts as both a stimulant and psychedelic, producing distorted sensory perceptions and feelings or altered states of awareness or sometimes states resembling psychosis (a severe mental disorder in which contact with reality is lost or highly distorted). MDMA is able to effect the inter-neuronal communication which uses serotonin, a neurotransmitter. The serotonin system has a crucial role in regulating aggression, mood, sexual activity, sleep, and sensitivity to pain. Thus the excessive use of MDMA is considered unsafe. Sweat testing can be performed for the detection of MDMA. MDMA test or the ecstasy test can be performed in various ways: either MDMA and its metabolites can be detected in sweat samples or a urine test can be performed. Sweat samples can be collected for next 24 hours after MDMA consumption although the drug metabolites may appear in the sweat right after 1.5 hours. In case the consumed MDMA quantity was very low, there are chances that the metabolites may get reduced and hard to detect with time. The MDMA test is also based on conventional immunoscreening and GC/MS analysis.

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